Food energy is also excreted from the system in the form of stool. In fact, the very act we are most concerned about-eating-puts energy into the system. Energy is constantly entering and leaving. This law is often invoked to support the Calories In/Calories Out model.īut thermodynamics, a law of physics, has minimal relevance to human biology for the simple reason that the human body is not an isolated system. The First Law of Thermodynamics states that energy can neither be created nor destroyed in an isolated system. There we have the real disease, and treatment must be directed against the ultimate, rather than the proximate cause.Ĭalories In – Calories Out = Body Fat If Calories Out remains stable over time, then reducing Calories In should produce weight loss. They may all contribute to varying degrees. But all chronic diseases are multifactorial, and these factors are not mutually exclusive.
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